Greater Response to Placebo in Children Than in Adults: A Systematic Review and Meta-Analysis in Drug-Resistant Partial Epilepsy

BACKGROUND: Despite guidelines establishing the need to perform comprehensive paediatric drug development programs, pivotal trials in children with epilepsy have been completed mostly in Phase IV as a postapproval replication of adult data. However, it has been shown that the treatment response in c...

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Detalles Bibliográficos
Autores principales: Rheims, Sylvain, Cucherat, Michel, Arzimanoglou, Alexis, Ryvlin, Philippe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504483/
https://www.ncbi.nlm.nih.gov/pubmed/18700812
http://dx.doi.org/10.1371/journal.pmed.0050166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504483/
https://www.ncbi.nlm.nih.gov/pubmed/18700812
http://dx.doi.org/10.1371/journal.pmed.0050166

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