GroEL as a molecular scaffold for structural analysis of the anthrax toxin pore

We analyzed the 440-kDa transmembrane pore formed by the protective antigen (PA) moiety of anthrax toxin in the presence of GroEL by negative-stain electron microscopy. GroEL binds both the heptameric PA prepore and the PA pore. The latter interaction retards aggregation of the pore, prolonging its...

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Detalles Bibliográficos
Autores principales: Katayama, Hiroo, Janowiak, Blythe E, Brzozowski, Marek, Juryck, Jordan, Falke, Scott, Gogol, Edward P, Collier, R John, Fisher, Mark T
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504863/
https://www.ncbi.nlm.nih.gov/pubmed/18568038
http://dx.doi.org/10.1038/nsmb.1442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504863/
https://www.ncbi.nlm.nih.gov/pubmed/18568038
http://dx.doi.org/10.1038/nsmb.1442

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