Cargando…

GroEL as a molecular scaffold for structural analysis of the anthrax toxin pore

We analyzed the 440-kDa transmembrane pore formed by the protective antigen (PA) moiety of anthrax toxin in the presence of GroEL by negative-stain electron microscopy. GroEL binds both the heptameric PA prepore and the PA pore. The latter interaction retards aggregation of the pore, prolonging its...

Descripción completa

Detalles Bibliográficos
Autores principales:	Katayama, Hiroo, Janowiak, Blythe E, Brzozowski, Marek, Juryck, Jordan, Falke, Scott, Gogol, Edward P, Collier, R John, Fisher, Mark T
Formato:	Texto
Lenguaje:	English
Publicado:	2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504863/ https://www.ncbi.nlm.nih.gov/pubmed/18568038 http://dx.doi.org/10.1038/nsmb.1442

Ejemplares similares

Cys−Cys Cross-Linking Shows Contact between the N-Terminus of Lethal Factor and Phe427 of the Anthrax Toxin Pore
por: Janowiak, Blythe E., et al.
Publicado: (2011)

Creating the Functional Single-Ring GroEL-GroES Chaperonin Systems via Modulating GroEL-GroES Interaction
por: Illingworth, Melissa, et al.
Publicado: (2017)

Myxococcus xanthus DK1622 Coordinates Expressions of the Duplicate groEL and Single groES Genes for Synergistic Functions of GroELs and GroES
por: Zhuo, Li, et al.
Publicado: (2017)

Back to GroEL-Assisted Protein Folding: GroES Binding-Induced Displacement of Denatured Proteins from GroEL to Bulk Solution
por: Marchenkov, Victor, et al.
Publicado: (2020)

Markov propagation of allosteric effects in biomolecular systems: application to GroEL–GroES
por: Chennubhotla, Chakra, et al.
Publicado: (2006)

Transient conformational remodeling of folding proteins by GroES—individually and in concert with GroEL
por: Moparthi, Satish Babu, et al.
Publicado: (2013)

Functional Differences between E. coli and ESKAPE Pathogen GroES/GroEL
por: Sivinski, Jared, et al.
Publicado: (2021)

Novel cryo-EM structure of an ADP-bound GroEL–GroES complex
por: Kudryavtseva, Sofia S., et al.
Publicado: (2021)

B-Cell Epitopes in GroEL of Francisella tularensis
por: Lu, Zhaohua, et al.
Publicado: (2014)

Dataset concerning GroEL chaperonin interaction with proteins
por: Marchenkov, V.V., et al.
Publicado: (2016)

Folding of maltose binding protein outside of and in GroEL
por: Ye, Xiang, et al.
Publicado: (2018)

The Chaperonin GroEL: A Versatile Tool for Applied Biotechnology Platforms
por: O'Neil, Pierce T., et al.
Publicado: (2018)

Topologies of a Substrate Protein Bound to the Chaperonin GroEL
por: Elad, Nadav, et al.
Publicado: (2007)

Probing the Dynamic Process of Encapsulation in Escherichia coli GroEL
por: Mizuta, Toshifumi, et al.
Publicado: (2013)

Suppression of amyloid fibrils using the GroEL apical domain
por: Ojha, Bimlesh, et al.
Publicado: (2016)

Probing Water Density and Dynamics in the Chaperonin GroEL Cavity
por: Franck, John M., et al.
Publicado: (2014)

GroEL is an immunodominant surface-exposed antigen of Rickettsia typhi
por: Rauch, Jessica, et al.
Publicado: (2021)

Structural and Computational Study of the GroEL–Prion Protein Complex
por: Mamchur, Aleksandra A., et al.
Publicado: (2021)

Folding of newly translated membrane protein CCR5 is assisted by the chaperonin GroEL-GroES
por: Chi, Haixia, et al.
Publicado: (2015)

Atomic structure of anthrax PA pore elucidates toxin translocation
por: Jiang, Jiansen, et al.
Publicado: (2015)

In vivo client proteins of the chaperonin GroEL-GroES provide insight into the role of chaperones in protein evolution
por: Taguchi, Hideki, et al.
Publicado: (2023)

Self-assembly of the chaperonin GroEL nanocage induced at submicellar detergent
por: Chen, Jin, et al.
Publicado: (2014)

Immunization Using GroEL Decreases Clostridium difficile Intestinal Colonization
por: Péchiné, Séverine, et al.
Publicado: (2013)

Chaperonin GroEL Reassembly: An Effect of Protein Ligands and Solvent Composition
por: Ryabova, Nataliya, et al.
Publicado: (2014)

Borrelia burgdorferi Surface Exposed GroEL Is a Multifunctional Protein
por: Cafiero, Thomas, et al.
Publicado: (2021)

GroEL Chaperonin-Based Assay for Early Diagnosis of Scrub Typhus
por: Indrawattana, Nitaya, et al.
Publicado: (2022)

Protein chain collapse modulation and folding stimulation by GroEL-ES
por: Naqvi, Mohsin M., et al.
Publicado: (2022)

Slowdown of Water Dynamics from the Top to the Bottom of the GroEL Cavity
por: Macro, Nicolas, et al.
Publicado: (2021)

GroEL—A Versatile Chaperone for Engineering and a Plethora of Applications
por: Yurkova, Maria S., et al.
Publicado: (2022)

GroEL-Proteotyping of Bacterial Communities Using Tandem Mass Spectrometry
por: Klaes, Simon, et al.
Publicado: (2023)

Roles of Anthrax Toxin Receptor 2 in Anthrax Toxin Membrane Insertion and Pore Formation
por: Sun, Jianjun, et al.
Publicado: (2016)

Asymmetric Cryo-EM Structure of Anthrax Toxin Protective Antigen Pore with Lethal Factor N-Terminal Domain
por: Machen, Alexandra J., et al.
Publicado: (2017)

Multi-Scale Simulations Provide Supporting Evidence for the Hypothesis of Intramolecular Protein Translocation in GroEL/GroES Complexes
por: Coluzza, Ivan, et al.
Publicado: (2008)

The Mycobacterium tuberculosis sRNA F6 Modifies Expression of Essential Chaperonins, GroEL2 and GroES
por: Houghton, Joanna, et al.
Publicado: (2021)

Probing the Functional Mechanism of Escherichia coli GroEL Using Circular Permutation
por: Mizobata, Tomohiro, et al.
Publicado: (2011)

GroEL actively stimulates folding of the endogenous substrate protein PepQ
por: Weaver, Jeremy, et al.
Publicado: (2017)

Measuring protein stability in the GroEL chaperonin cage reveals massive destabilization
por: Korobko, Ilia, et al.
Publicado: (2020)

Production of a toxic polypeptide as a fusion inside GroEL cavity
por: Yurkova, Maria S., et al.
Publicado: (2020)

Dissecting the Thermodynamics of ATP Binding to GroEL One Nucleotide at a Time
por: Walker, Thomas, et al.
Publicado: (2023)

Functions of Phenylalanine Residues within the β-Barrel Stem of the Anthrax Toxin Pore
por: Wang, Jie, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_h0kc1o9eu3ouojpg565kc2pulc