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Modeling ChIP Sequencing In Silico with Applications

ChIP sequencing (ChIP-seq) is a new method for genomewide mapping of protein binding sites on DNA. It has generated much excitement in functional genomics. To score data and determine adequate sequencing depth, both the genomic background and the binding sites must be properly modeled. To develop a...

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Detalles Bibliográficos
Autores principales: Zhang, Zhengdong D., Rozowsky, Joel, Snyder, Michael, Chang, Joseph, Gerstein, Mark
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2507756/
https://www.ncbi.nlm.nih.gov/pubmed/18725927
http://dx.doi.org/10.1371/journal.pcbi.1000158