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Modeling ChIP Sequencing In Silico with Applications
ChIP sequencing (ChIP-seq) is a new method for genomewide mapping of protein binding sites on DNA. It has generated much excitement in functional genomics. To score data and determine adequate sequencing depth, both the genomic background and the binding sites must be properly modeled. To develop a...
Autores principales: | Zhang, Zhengdong D., Rozowsky, Joel, Snyder, Michael, Chang, Joseph, Gerstein, Mark |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2507756/ https://www.ncbi.nlm.nih.gov/pubmed/18725927 http://dx.doi.org/10.1371/journal.pcbi.1000158 |
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