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The Association of C-Reactive Protein and CRP Genotype with Coronary Heart Disease: Findings from Five Studies with 4,610 Cases amongst 18,637 Participants

BACKGROUND: It is unclear whether C-reactive protein (CRP) is causally related to coronary heart disease (CHD). Genetic variants that are known to be associated with CRP levels can be used to provide causal inference of the effect of CRP on CHD. Our objective was to examine the association between C...

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Detalles Bibliográficos
Autores principales: Lawlor, Debbie A., Harbord, Roger M., Timpson, Nic J., Lowe, Gordon D. O., Rumley, Ann, Gaunt, Tom R., Baker, Ian, Yarnell, John W. G., Kivimäki, Mika, Kumari, Meena, Norman, Paul E., Jamrozik, Konrad, Hankey, Graeme J., Almeida, Osvaldo P., Flicker, Leon, Warrington, Nicole, Marmot, Michael G., Ben-Shlomo, Yoav, Palmer, Lyle J., Day, Ian N. M., Ebrahim, Shah, Smith, George Davey
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2507759/
https://www.ncbi.nlm.nih.gov/pubmed/18714384
http://dx.doi.org/10.1371/journal.pone.0003011