Activation of Ubiquitin-Dependent DNA Damage Bypass Is Mediated by Replication Protein A

Replicative DNA damage bypass, mediated by the ubiquitylation of the sliding clamp protein PCNA, facilitates the survival of a cell in the presence of genotoxic agents, but it can also promote genomic instability by damage-induced mutagenesis. We show here that PCNA ubiquitylation in budding yeast i...

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Detalles Bibliográficos
Autores principales: Davies, Adelina A., Huttner, Diana, Daigaku, Yasukazu, Chen, Shuhua, Ulrich, Helle D.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2507760/
https://www.ncbi.nlm.nih.gov/pubmed/18342608
http://dx.doi.org/10.1016/j.molcel.2007.12.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2507760/
https://www.ncbi.nlm.nih.gov/pubmed/18342608
http://dx.doi.org/10.1016/j.molcel.2007.12.016

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