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Activation of Ubiquitin-Dependent DNA Damage Bypass Is Mediated by Replication Protein A
Replicative DNA damage bypass, mediated by the ubiquitylation of the sliding clamp protein PCNA, facilitates the survival of a cell in the presence of genotoxic agents, but it can also promote genomic instability by damage-induced mutagenesis. We show here that PCNA ubiquitylation in budding yeast i...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2507760/ https://www.ncbi.nlm.nih.gov/pubmed/18342608 http://dx.doi.org/10.1016/j.molcel.2007.12.016 |