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A general method for phasing novel complex RNA crystal structures without heavy-atom derivatives

The crystallographic phase problem [Muirhead & Perutz (1963 ▶), Nature (London), 199, 633–638] remains the single major impediment to obtaining a three-dimensional structure of a macromolecule once suitable crystals have been obtained. Recently, it was found that it was possible to solve the str...

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Detalles Bibliográficos
Autores principales: Robertson, Michael P., Scott, William G.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2507861/
https://www.ncbi.nlm.nih.gov/pubmed/18566509
http://dx.doi.org/10.1107/S0907444908011578