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A general method for phasing novel complex RNA crystal structures without heavy-atom derivatives
The crystallographic phase problem [Muirhead & Perutz (1963 ▶), Nature (London), 199, 633–638] remains the single major impediment to obtaining a three-dimensional structure of a macromolecule once suitable crystals have been obtained. Recently, it was found that it was possible to solve the str...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2507861/ https://www.ncbi.nlm.nih.gov/pubmed/18566509 http://dx.doi.org/10.1107/S0907444908011578 |