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Perhalogenated pyrimidine scaffolds. Reactions of 5-chloro-2,4,6-trifluoropyrimidine with nitrogen centred nucleophiles

BACKGROUND: Highly functionalised pyrimidine derivatives are of great importance to the life-science industries and there exists a need for efficient synthetic methodology that allows the synthesis of polysubstituted pyrimidine derivatives that are regioselective in all stages to meet the demands of...

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Detalles Bibliográficos
Autores principales: Parks, Emma L, Sandford, Graham, Christopher, John A, Miller, David D
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2511021/
https://www.ncbi.nlm.nih.gov/pubmed/18941492
http://dx.doi.org/10.3762/bjoc.4.22