Topology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selection

BACKGROUND: The molecular events and evolutionary forces underlying lethal mutagenesis of virus (or virus extinction through an excess of mutations) are not well understood. Here we apply for the first time phylogenetic methods and Partition Analysis of Quasispecies (PAQ) to monitor genetic distance...

Descripción completa

Detalles Bibliográficos
Autores principales: Ojosnegros, Samuel, Agudo, Rubén, Sierra, Macarena, Briones, Carlos, Sierra, Saleta, González- López, Claudia, Domingo, Esteban, Cristina, Juan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515104/
https://www.ncbi.nlm.nih.gov/pubmed/18637173
http://dx.doi.org/10.1186/1471-2148-8-207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515104/
https://www.ncbi.nlm.nih.gov/pubmed/18637173
http://dx.doi.org/10.1186/1471-2148-8-207

Ejemplares similares