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Topology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selection
BACKGROUND: The molecular events and evolutionary forces underlying lethal mutagenesis of virus (or virus extinction through an excess of mutations) are not well understood. Here we apply for the first time phylogenetic methods and Partition Analysis of Quasispecies (PAQ) to monitor genetic distance...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515104/ https://www.ncbi.nlm.nih.gov/pubmed/18637173 http://dx.doi.org/10.1186/1471-2148-8-207 |