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On the origins of arrestin and rhodopsin
BACKGROUND: G protein coupled receptors (GPCRs) are the most numerous proteins in mammalian genomes, and the most common targets of clinical drugs. However, their evolution remains enigmatic. GPCRs are intimately associated with trimeric G proteins, G protein receptor kinases, and arrestins. We cond...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515105/ https://www.ncbi.nlm.nih.gov/pubmed/18664266 http://dx.doi.org/10.1186/1471-2148-8-222 |