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On the origins of arrestin and rhodopsin

BACKGROUND: G protein coupled receptors (GPCRs) are the most numerous proteins in mammalian genomes, and the most common targets of clinical drugs. However, their evolution remains enigmatic. GPCRs are intimately associated with trimeric G proteins, G protein receptor kinases, and arrestins. We cond...

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Detalles Bibliográficos
Autor principal: Alvarez, Carlos E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515105/
https://www.ncbi.nlm.nih.gov/pubmed/18664266
http://dx.doi.org/10.1186/1471-2148-8-222