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Inference of Protein Complex Activities from Chemical-Genetic Profile and Its Applications: Predicting Drug-Target Pathways

The chemical-genetic profile can be defined as quantitative values of deletion strains' growth defects under exposure to chemicals. In yeast, the compendium of chemical-genetic profiles of genomewide deletion strains under many different chemicals has been used for identifying direct target pro...

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Detalles Bibliográficos
Autores principales: Han, Sangjo, Kim, Dongsup
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515108/
https://www.ncbi.nlm.nih.gov/pubmed/18769708
http://dx.doi.org/10.1371/journal.pcbi.1000162