Cargando…

An Sp1/Sp3 Binding Polymorphism Confers Methylation Protection

Hundreds of genes show aberrant DNA hypermethylation in cancer, yet little is known about the causes of this hypermethylation. We identified RIL as a frequent methylation target in cancer. In search for factors that influence RIL hypermethylation, we found a 12-bp polymorphic sequence around its tra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boumber, Yanis A., Kondo, Yutaka, Chen, Xuqi, Shen, Lanlan, Guo, Yi, Tellez, Carmen, Estécio, Marcos R. H., Ahmed, Saira, Issa, Jean-Pierre J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515197/ https://www.ncbi.nlm.nih.gov/pubmed/18725933 http://dx.doi.org/10.1371/journal.pgen.1000162

Ejemplares similares

DNA Methylation Profiles of Primary Colorectal Carcinoma and Matched Liver Metastasis
por: Konishi, Kazuo, et al.
Publicado: (2011)

Downregulation of Histone H3 Lysine 9 Methyltransferase G9a Induces Centrosome Disruption and Chromosome Instability in Cancer Cells
por: Kondo, Yutaka, et al.
Publicado: (2008)

Tackling the methylome: recent methodological advances in genome-wide methylation profiling
por: Estécio, Marcos RH, et al.
Publicado: (2009)

Repetitive elements and enforced transcriptional repression co-operate to enhance DNA methylation spreading into a promoter CpG-island
por: Zhang, Yan, et al.
Publicado: (2012)

Genome-Wide Profiling of DNA Methylation Reveals a Class of Normally Methylated CpG Island Promoters
por: Shen, Lanlan, et al.
Publicado: (2007)

Bioaccumulation of Total and Methyl Mercury in Three Earthworm Species (Drawida sp., Allolobophora sp., and Limnodrilus sp.)
por: Zhang, Zhong Sheng, et al.
Publicado: (2009)

Genetic Polymorphisms of SP-A, SP-B, and SP-D and Risk of Respiratory Distress Syndrome in Preterm Neonates
por: Chang, Hong-Yu, et al.
Publicado: (2016)

Relevance of Sp Binding Site Polymorphism in WWOX for Treatment Outcome in Pancreatic Cancer
por: Schirmer, Markus A., et al.
Publicado: (2016)

SP-D Polymorphisms and the Risk of COPD
por: Shakoori, Tania A., et al.
Publicado: (2012)

TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells
por: Jin, Chunlei, et al.
Publicado: (2014)

Vaccination against Influenza with Recombinant Hemagglutinin Expressed by Schizochytrium sp. Confers Protective Immunity
por: Bayne, Anne-Cécile V., et al.
Publicado: (2013)

Reciprocal Role Of DNA Methylation And Sp1 Binding In Ki-67 Gene Transcription
por: Li, Lian-Tao, et al.
Publicado: (2019)

Microsoft Exchange Server 2003: Scalability with SP1 and SP2
por: Bijaoui, Pierre
Publicado: (2006)

Aberrant DNA Methylation Is Associated with Disease Progression, Resistance to Imatinib and Shortened Survival in Chronic Myelogenous Leukemia
por: Jelinek, Jaroslav, et al.
Publicado: (2011)

Certain Polymorphisms in SP110 Gene Confer Susceptibility to Tuberculosis: A Comprehensive Review and Updated Meta-Analysis
por: Zhang, Shuai, et al.
Publicado: (2017)

CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383
por: Reynard, Louise N., et al.
Publicado: (2014)

The sea urchin metallothionein system: Comparative evaluation of the SpMTA and SpMTB metal-binding preferences()
por: Tomas, Mireia, et al.
Publicado: (2013)

Loss of TIMP3 by promoter methylation of Sp1 binding site promotes oral cancer metastasis
por: Su, Chun-Wen, et al.
Publicado: (2019)

Physiological TLR5 expression in the intestine is regulated by differential DNA binding of Sp1/Sp3 through simultaneous Sp1 dephosphorylation and Sp3 phosphorylation by two different PKC isoforms
por: Thakur, Bhupesh Kumar, et al.
Publicado: (2016)

Chryseobacterium potabilaquae sp. nov., Chryseobacterium aquaeductus sp. nov. and Chryseobacterium fistulae sp. nov., from drinking water systems
por: Lucena, Teresa, et al.
Publicado: (2021)

Description of Three Novel Members in the Family Geobacteraceae, Oryzomonas japonicum gen. nov., sp. nov., Oryzomonas sagensis sp. nov., and Oryzomonas ruber sp. nov.
por: Xu, Zhenxing, et al.
Publicado: (2020)

Polymorphism of a COLIA1 Gene Sp1 Binding Site in Korean Women with Pelvic Organ Prolapse
por: Cho, Hye Jin, et al.
Publicado: (2009)

Case report: reinitiating pembrolizumab treatment after small bowel perforation
por: Beck, Tim N., et al.
Publicado: (2019)

Tumor-Targeted Drug Conjugates as an Emerging Novel Therapeutic Approach in Small Cell Lung Cancer (SCLC)
por: Deneka, Alexander Y., et al.
Publicado: (2019)

NSD1 supports cell growth and regulates autophagy in HPV-negative head and neck squamous cell carcinoma
por: Topchu, Iuliia, et al.
Publicado: (2023)

Draft Genome Sequences of Five Neonatal Meningitis-Causing Escherichia coli Isolates (SP-4, SP-5, SP-13, SP-46, and SP-65)
por: Xu, Aixia, et al.
Publicado: (2018)

Zinc Finger Independent Genome-Wide Binding of Sp2 Potentiates Recruitment of Histone-Fold Protein Nf-y Distinguishing It from Sp1 and Sp3
por: Völkel, Sara, et al.
Publicado: (2015)

Actinobacteria Associated with the Marine Sponges Cinachyra sp., Petrosia sp., and Ulosa sp. and Their Culturability
por: Khan, Shams Tabrez, et al.
Publicado: (2012)

Alterations of Bacteroides sp., Neisseria sp., Actinomyces sp., and Streptococcus sp. populations in the oropharyngeal microbiome are associated with liver cirrhosis and pneumonia
por: Lu, Haifeng, et al.
Publicado: (2015)

Alkaliphilus flagellatus sp. nov., Butyricicoccus intestinisimiae sp. nov., Clostridium mobile sp. nov., Clostridium simiarum sp. nov., Dysosmobacter acutus sp. nov., Paenibacillus brevis sp. nov., Peptoniphilus ovalis sp. nov. and Tissierella simiarum sp. nov., isolated from monkey faeces
por: Li, Dan-Hua, et al.
Publicado: (2022)

Alumination of aryl methyl ethers: switching between sp(2) and sp(3) C–O bond functionalisation with Pd-catalysis
por: Brown, Ryan K., et al.
Publicado: (2021)

Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells
por: Hedrick, Erik, et al.
Publicado: (2016)

Different Antifungal Activity of Anabaena sp., Ecklonia sp., and Jania sp. against Botrytis cinerea
por: Righini, Hillary, et al.
Publicado: (2019)

Yersinia artesiana sp. nov., Yersinia proxima sp. nov., Yersinia alsatica sp. nov., Yersina vastinensis sp. nov., Yersinia thracica sp. nov. and Yersinia occitanica sp. nov., isolated from humans and animals
por: Le Guern, Anne-Sophie, et al.
Publicado: (2020)

Description of ‘Bacillus dakarensis’ sp. nov., ‘Bacillus sinesaloumensis’ sp. nov., ‘Gracilibacillus timonensis’ sp. nov., ‘Halobacillus massiliensis’ sp. nov., ‘Lentibacillus massiliensis’ sp. nov., ‘Oceanobacillus senegalensis’ sp. nov., ‘Oceanobacillus timonensis’ sp. nov., ‘Virgibacillus dakarensis’ sp. nov. and ‘Virgibacillus marseillensis’ sp. nov., nine halophilic new species isolated from human stool
por: Senghor, B., et al.
Publicado: (2017)

Conserved Surface Accessible Nucleoside ABC Transporter Component SP0845 Is Essential for Pneumococcal Virulence and Confers Protection In Vivo
por: Saxena, Sneha, et al.
Publicado: (2015)

Emerging Applications of Chlorella sp. and Spirulina (Arthrospira) sp.
por: Abreu, Ana P., et al.
Publicado: (2023)

Frequent Alteration of MLL3 Frameshift Mutations in Microsatellite Deficient Colorectal Cancer
por: Watanabe, Yoshiyuki, et al.
Publicado: (2011)

Ni(II) Interactions in Boreal Paenibacillus sp., Methylobacterium sp., Paraburkholderia sp., and Pseudomonas sp. Strains Isolated From an Acidic, Ombrotrophic Bog
por: Knuutinen, Jenna, et al.
Publicado: (2019)

Lactobacillus apinorum sp. nov., Lactobacillus mellifer sp. nov., Lactobacillus mellis sp. nov., Lactobacillus melliventris sp. nov., Lactobacillus kimbladii sp. nov., Lactobacillus helsingborgensis sp. nov. and Lactobacillus kullabergensis sp. nov., isolated from the honey stomach of the honeybee Apis mellifera
por: Olofsson, Tobias C., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_9p9hfg1iir6nnjakscd0e1ebev