Cargando…

The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease

Recent evidence supports a neuroprotective role for Wnt signaling in neurodegenerative disorders such as Alzheimer's Disease (AD). In fact, a relationship between amyloid-β-peptide (Aβ)-induced neurotoxicity and a decrease in the cytoplasmic levels of β-catenin has been observed. Apparently Aβ...

Descripción completa

Detalles Bibliográficos
Autores principales: Inestrosa, Nibaldo C, Toledo, Enrique M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515306/
https://www.ncbi.nlm.nih.gov/pubmed/18652670
http://dx.doi.org/10.1186/1750-1326-3-9