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In Vitro Analysis of Integrated Global High-Resolution DNA Methylation Profiling with Genomic Imbalance and Gene Expression in Osteosarcoma

Genetic and epigenetic changes contribute to deregulation of gene expression and development of human cancer. Changes in DNA methylation are key epigenetic factors regulating gene expression and genomic stability. Recent progress in microarray technologies resulted in developments of high resolution...

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Detalles Bibliográficos
Autores principales: Sadikovic, Bekim, Yoshimoto, Maisa, Al-Romaih, Khaldoun, Maire, Georges, Zielenska, Maria, Squire, Jeremy A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515339/
https://www.ncbi.nlm.nih.gov/pubmed/18698372
http://dx.doi.org/10.1371/journal.pone.0002834