Liposomal Packaging Generates Wnt Protein with In Vivo Biological Activity

Wnt signals exercise strong cell-biological and regenerative effects of considerable therapeutic value. There are, however, no specific Wnt agonists and no method for in vivo delivery of purified Wnt proteins. Wnts contain lipid adducts that are required for activity and we exploited this lipophilic...

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Detalles Bibliográficos
Autores principales: Morrell, Nathan T., Leucht, Philipp, Zhao, Ludan, Kim, Jae-Beom, ten Berge, Derk, Ponnusamy, Karthik, Carre, A. Lyonel, Dudek, Henryk, Zachlederova, Marie, McElhaney, Michael, Brunton, Shirley, Gunzner, Janet, Callow, Marinella, Polakis, Paul, Costa, Mike, Zhang, Xiaoyan M., Helms, Jill A., Nusse, Roel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515347/
https://www.ncbi.nlm.nih.gov/pubmed/18698373
http://dx.doi.org/10.1371/journal.pone.0002930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515347/
https://www.ncbi.nlm.nih.gov/pubmed/18698373
http://dx.doi.org/10.1371/journal.pone.0002930

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