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Promoter polymorphisms of DNMT3B and the risk of colorectal cancer in Chinese: a case-control study
BACKGROUND: DNA-methyltransferase-3B (DNMT3B), which plays a role in DNA methylation, is usually aberrant expression involved in carcinogenesis. Polymorphisms of the DNMT3B gene may influence DNMT3B activity on DNA methylation in several cancers, thereby modulating the susceptibility to cancer. METH...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515831/ https://www.ncbi.nlm.nih.gov/pubmed/18662374 http://dx.doi.org/10.1186/1756-9966-27-24 |