Cargando…

Promoter polymorphisms of DNMT3B and the risk of colorectal cancer in Chinese: a case-control study

BACKGROUND: DNA-methyltransferase-3B (DNMT3B), which plays a role in DNA methylation, is usually aberrant expression involved in carcinogenesis. Polymorphisms of the DNMT3B gene may influence DNMT3B activity on DNA methylation in several cancers, thereby modulating the susceptibility to cancer. METH...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Hong, Zhang, Feng, Hu, Jiabo, Liu, Dongsheng, Zhao, Zhujiang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515831/
https://www.ncbi.nlm.nih.gov/pubmed/18662374
http://dx.doi.org/10.1186/1756-9966-27-24