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P53 expression is significantly correlated with high risk of malignancy and epithelioid differentiation in GISTs. An immunohistochemical study of 104 cases

BACKGROUND: Molecular analyses of the c-kit and PDGFRα genes have contributed greatly to our understanding of the development of gastrointestinal stromal tumors (GISTs), but little is known about their malignant potential. The aim of our study was to evaluate cell cycle regulators as potential progn...

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Detalles Bibliográficos
Autores principales: Pauser, Ursula, Schmedt auf der Günne, Nina, Klöppel, Günter, Merz, Hartmut, Feller, Alfred C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515850/
https://www.ncbi.nlm.nih.gov/pubmed/18651966
http://dx.doi.org/10.1186/1471-2407-8-204