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Reduced tricarboxylic acid cycle flux in type 2 diabetes mellitus?

AIMS/HYPOTHESIS: Mitochondrial dysfunction has been postulated to underlie muscular fat accumulation, leading to muscular insulin sensitivity and ultimately type 2 diabetes mellitus. Here we re-interpret previously published data on [(13)C]acetate recovery in breath gas obtained during exercise in t...

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Detalles Bibliográficos
Autores principales: Schrauwen, P., Hesselink, M. K. C.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516188/
https://www.ncbi.nlm.nih.gov/pubmed/18587560
http://dx.doi.org/10.1007/s00125-008-1069-x