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Molecular composition of the peri-islet basement membrane in NOD mice: a barrier against destructive insulitis

AIMS/HYPOTHESIS: This study examined whether the capsule which encases islets of Langerhans in the NOD mouse pancreas represents a specialised extracellular matrix (ECM) or basement membrane that protects islets from autoimmune attack. METHODS: Immunofluorescence microscopy using a panel of antibodi...

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Detalles Bibliográficos
Autores principales: Irving-Rodgers, H. F., Ziolkowski, A. F., Parish, C. R., Sado, Y., Ninomiya, Y., Simeonovic, C. J., Rodgers, R. J.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516190/
https://www.ncbi.nlm.nih.gov/pubmed/18633594
http://dx.doi.org/10.1007/s00125-008-1085-x