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Induction of Blood Brain Barrier Tight Junction Protein Alterations by CD8 T Cells

Disruption of the blood brain barrier (BBB) is a hallmark feature of immune-mediated neurological disorders as diverse as viral hemorrhagic fevers, cerebral malaria and acute hemorrhagic leukoencephalitis. Although current models hypothesize that immune cells promote vascular permeability in human d...

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Detalles Bibliográficos
Autores principales: Suidan, Georgette L., Mcdole, Jeremiah R., Chen, Yi, Pirko, Istvan, Johnson, Aaron J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516328/
https://www.ncbi.nlm.nih.gov/pubmed/18725947
http://dx.doi.org/10.1371/journal.pone.0003037