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Optical mapping discerns genome wide DNA methylation profiles

BACKGROUND: Methylation of CpG dinucleotides is a fundamental mechanism of epigenetic regulation in eukaryotic genomes. Development of methods for rapid genome wide methylation profiling will greatly facilitate both hypothesis and discovery driven research in the field of epigenetics. In this regard...

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Detalles Bibliográficos
Autores principales: Ananiev, Gene E, Goldstein, Steve, Runnheim, Rod, Forrest, Dan K, Zhou, Shiguo, Potamousis, Konstantinos, Churas, Chris P, Bergendahl, Veit, Thomson, James A, Schwartz, David C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516518/
https://www.ncbi.nlm.nih.gov/pubmed/18667073
http://dx.doi.org/10.1186/1471-2199-9-68