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Optical mapping discerns genome wide DNA methylation profiles
BACKGROUND: Methylation of CpG dinucleotides is a fundamental mechanism of epigenetic regulation in eukaryotic genomes. Development of methods for rapid genome wide methylation profiling will greatly facilitate both hypothesis and discovery driven research in the field of epigenetics. In this regard...
Autores principales: | Ananiev, Gene E, Goldstein, Steve, Runnheim, Rod, Forrest, Dan K, Zhou, Shiguo, Potamousis, Konstantinos, Churas, Chris P, Bergendahl, Veit, Thomson, James A, Schwartz, David C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516518/ https://www.ncbi.nlm.nih.gov/pubmed/18667073 http://dx.doi.org/10.1186/1471-2199-9-68 |
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