Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin

BACKGROUND: Bowing and/or pseudarthrosis of the tibia is a known severe complication of neurofibromatosis type 1 (NF1). Mice with conditionally inactivated neurofibromin (Nf1) in the developing limbs and cranium (Nf1Prx1) show bowing of the tibia caused by decreased bone mineralisation and increased...

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Detalles Bibliográficos
Autores principales: Kolanczyk, Mateusz, Kühnisch, Jirko, Kossler, Nadine, Osswald, Monika, Stumpp, Sabine, Thurisch, Boris, Kornak, Uwe, Mundlos, Stefan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516519/
https://www.ncbi.nlm.nih.gov/pubmed/18671844
http://dx.doi.org/10.1186/1741-7015-6-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516519/
https://www.ncbi.nlm.nih.gov/pubmed/18671844
http://dx.doi.org/10.1186/1741-7015-6-21

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