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Effects of COX-2 inhibition on expression of vascular endothelial growth factor and interleukin-8 in lung cancer cells

BACKGROUND: Cyclooxygenase (COX)-2 has been implicated in tumour progression, angiogenesis and metastasis in non-small cell lung cancer (NSCLC). We speculated that inhibition of COX-2 activity might reduce expression of the pro-angiogenic factors vascular endothelial growth factor (VEGF) and interle...

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Detalles Bibliográficos
Autores principales: Zhu, Yong Ming, Azahri, Nor Saadah M, Yu, Danny CW, Woll, Penella J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516523/
https://www.ncbi.nlm.nih.gov/pubmed/18671849
http://dx.doi.org/10.1186/1471-2407-8-218