The fraction of activated N-methyl-d-Aspartate receptors during synaptic transmission remains constant in the presence of the glutamate release inhibitor riluzole

Excessive N-methyl-d-aspartate (NMDA) receptor activation is widely accepted to mediate calcium-dependent glutamate excitotoxicity. The uncompetitive, voltage-dependent NMDA receptor antagonist memantine has been successfully used clinically in the treatment of neurodegenerative dementia and is inte...

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Detalles Bibliográficos
Autores principales: Rammes, G., Zieglgänsberger, W., Parsons, C. G.
Formato: Texto
Lenguaje:English
Publicado: Springer Vienna 2008
Materias:
Basic Neurosciences, Genetics and Immunology - Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516544/
https://www.ncbi.nlm.nih.gov/pubmed/18493706
http://dx.doi.org/10.1007/s00702-008-0059-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516544/
https://www.ncbi.nlm.nih.gov/pubmed/18493706
http://dx.doi.org/10.1007/s00702-008-0059-y

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