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Computational Toxicology of Chloroform: Reverse Dosimetry Using Bayesian Inference, Markov Chain Monte Carlo Simulation, and Human Biomonitoring Data
BACKGROUND: One problem of interpreting population-based biomonitoring data is the reconstruction of corresponding external exposure in cases where no such data are available. OBJECTIVES: We demonstrate the use of a computational framework that integrates physiologically based pharmacokinetic (PBPK)...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516557/ https://www.ncbi.nlm.nih.gov/pubmed/18709138 http://dx.doi.org/10.1289/ehp.11079 |