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Computational Toxicology of Chloroform: Reverse Dosimetry Using Bayesian Inference, Markov Chain Monte Carlo Simulation, and Human Biomonitoring Data

BACKGROUND: One problem of interpreting population-based biomonitoring data is the reconstruction of corresponding external exposure in cases where no such data are available. OBJECTIVES: We demonstrate the use of a computational framework that integrates physiologically based pharmacokinetic (PBPK)...

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Detalles Bibliográficos
Autores principales: Lyons, Michael A., Yang, Raymond S.H., Mayeno, Arthur N., Reisfeld, Brad
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516557/
https://www.ncbi.nlm.nih.gov/pubmed/18709138
http://dx.doi.org/10.1289/ehp.11079