Genomic Profiling Reveals an Alternate Mechanism for Hepatic Tumor Promotion by Perfluorooctanoic Acid in Rainbow Trout

BACKGROUND: Perfluorooctanoic acid (PFOA) is a potent hepatocarcinogen and peroxisome proliferator (PP) in rodents. Humans are not susceptible to peroxisome proliferation and are considered refractory to carcinogenesis by PPs. Previous studies with rainbow trout indicate they are also insensitive to...

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Detalles Bibliográficos
Autores principales: Tilton, Susan C., Orner, Gayle A., Benninghoff, Abby D., Carpenter, Hillary M., Hendricks, Jerry D., Pereira, Cliff B., Williams, David E.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516568/
https://www.ncbi.nlm.nih.gov/pubmed/18709148
http://dx.doi.org/10.1289/ehp.11190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516568/
https://www.ncbi.nlm.nih.gov/pubmed/18709148
http://dx.doi.org/10.1289/ehp.11190

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