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The Critical Role of Partially Exposed N-Terminal Valine Residue in Stabilizing GH10 Xylanase from Bacillus sp.NG-27 under Poly-Extreme Conditions

BACKGROUND: Understanding the mechanisms that govern protein stability under poly-extreme conditions continues to be a major challenge. Xylanase (BSX) from Bacillus sp. NG-27, which has a TIM-barrel structure, shows optimum activity at high temperature and alkaline pH, and is resistant to denaturati...

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Detalles Bibliográficos
Autores principales: Bharadwaj, Amit, Leelavathi, Sadhu, Mazumdar-Leighton, Sudeshna, Ghosh, Amit, Ramakumar, Suryanarayanarao, Reddy, Vanga S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516601/
https://www.ncbi.nlm.nih.gov/pubmed/18725971
http://dx.doi.org/10.1371/journal.pone.0003063