JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells

Cytokines contribute to pancreatic β-cell apoptosis in type 1 diabetes (T1D) by modulation of β-cell gene expression networks. The transcription factor Activator Protein-1 (AP-1) is a key regulator of inflammation and apoptosis. We presently evaluated the function of the AP-1 subunit JunB in cytokin...

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Detalles Bibliográficos
Autores principales: Gurzov, Esteban N., Ortis, Fernanda, Bakiri, Latifa, Wagner, Erwin F., Eizirik, Decio L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516602/
https://www.ncbi.nlm.nih.gov/pubmed/18716665
http://dx.doi.org/10.1371/journal.pone.0003030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516602/
https://www.ncbi.nlm.nih.gov/pubmed/18716665
http://dx.doi.org/10.1371/journal.pone.0003030

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