A Feature-Based Approach to Modeling Protein–DNA Interactions

Transcription factor (TF) binding to its DNA target site is a fundamental regulatory interaction. The most common model used to represent TF binding specificities is a position specific scoring matrix (PSSM), which assumes independence between binding positions. However, in many cases, this simplify...

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Detalles Bibliográficos
Autores principales: Sharon, Eilon, Lubliner, Shai, Segal, Eran
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516605/
https://www.ncbi.nlm.nih.gov/pubmed/18725950
http://dx.doi.org/10.1371/journal.pcbi.1000154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516605/
https://www.ncbi.nlm.nih.gov/pubmed/18725950
http://dx.doi.org/10.1371/journal.pcbi.1000154

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