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Stochasticity and the Molecular Mechanisms of Induced Pluripotency

The generation of induced pluripotent stem cells from adult somatic cells by ectopic expression of key transcription factors holds significant medical promise. However, current techniques for inducing pluripotency rely on viral infection and are therefore not, at present, viable within a clinical se...

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Detalles Bibliográficos
Autores principales: MacArthur, Ben D., Please, Colin P., Oreffo, Richard O. C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517845/
https://www.ncbi.nlm.nih.gov/pubmed/18769478
http://dx.doi.org/10.1371/journal.pone.0003086