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FGF2 Translationally Induced by Hypoxia Is Involved in Negative and Positive Feedback Loops with HIF-1α

BACKGROUND: Fibroblast growth factor 2 (FGF2) is a major angiogenic factor involved in angiogenesis and arteriogenesis, however the regulation of its expression during these processes is poorly documented. FGF2 mRNA contains an internal ribosome entry site (IRES), a translational regulator expected...

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Detalles Bibliográficos
Autores principales: Conte, Caroline, Riant, Elodie, Toutain, Céline, Pujol, Françoise, Arnal, Jean-François, Lenfant, Françoise, Prats, Anne-Catherine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518102/
https://www.ncbi.nlm.nih.gov/pubmed/18728783
http://dx.doi.org/10.1371/journal.pone.0003078