Targeted Chromosomal Insertion of Large DNA into the Human Genome by a Fiber-Modified High-Capacity Adenovirus-Based Vector System

A prominent goal in gene therapy research concerns the development of gene transfer vehicles that can integrate exogenous DNA at specific chromosomal loci to prevent insertional oncogenesis and provide for long-term transgene expression. Adenovirus (Ad) vectors arguably represent the most efficient...

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Detalles Bibliográficos
Autores principales: Gonçalves, Manuel A. F. V., Holkers, Maarten, van Nierop, Gijsbert P., Wieringa, Roeland, Pau, Maria G., de Vries, Antoine A. F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518115/
https://www.ncbi.nlm.nih.gov/pubmed/18769728
http://dx.doi.org/10.1371/journal.pone.0003084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518115/
https://www.ncbi.nlm.nih.gov/pubmed/18769728
http://dx.doi.org/10.1371/journal.pone.0003084

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