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Interaction of the growth and tumour suppressor NORE1A with microtubules is not required for its growth-suppressive function

BACKGROUND: The NORE1 protein was identified in a yeast two-hybrid screen as a Ras effector that binds Ras protein in a GTP-dependent manner. NORE1A is a growth and tumour suppressor that is inactivated in a variety of cancers. In transformed human cells, both full-length NORE1A protein and its effe...

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Detalles Bibliográficos
Autores principales: Moshnikova, Anna, Kuznetsov, Sergey, Khokhlatchev, Andrei V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518271/
https://www.ncbi.nlm.nih.gov/pubmed/18710533
http://dx.doi.org/10.1186/1756-0500-1-13