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Interaction of the growth and tumour suppressor NORE1A with microtubules is not required for its growth-suppressive function
BACKGROUND: The NORE1 protein was identified in a yeast two-hybrid screen as a Ras effector that binds Ras protein in a GTP-dependent manner. NORE1A is a growth and tumour suppressor that is inactivated in a variety of cancers. In transformed human cells, both full-length NORE1A protein and its effe...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518271/ https://www.ncbi.nlm.nih.gov/pubmed/18710533 http://dx.doi.org/10.1186/1756-0500-1-13 |