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Review of the clinical evidence for interferon β 1a (Rebif(®)) in the treatment of multiple sclerosis

Interferon (INF) β 1a 22 or 44 μg (Rebif(®)) administered s.c. 3 times a week (t.i.w) is a well established immunomodulating treatment for relapsing remitting multiple sclerosis (RRMS). This review focuses on its mechanisms of action, evidence of efficacy, safety, and tolerability. Several pharmacod...

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Detalles Bibliográficos
Autores principales: Manfredonia, Francesco, Pasquali, Livia, Dardano, Angela, Iudice, Alfonso, Murri, Luigi, Monzani, Fabio
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518386/
https://www.ncbi.nlm.nih.gov/pubmed/18728744