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Intracerebroventricular Administration of Neuropeptide Y Induces Hepatic Insulin Resistance via Sympathetic Innervation

OBJECTIVE—We recently showed that intracerebroventricular infusion of neuropeptide Y (NPY) hampers inhibition of endogenous glucose production (EGP) by insulin in mice. The downstream mechanisms responsible for these effects of NPY remain to be elucidated. Therefore, the aim of this study was to est...

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Detalles Bibliográficos
Autores principales: van den Hoek, Anita M., van Heijningen, Caroline, Schröder-van der Elst, Janny P., Ouwens, D. Margriet, Havekes, Louis M., Romijn, Johannes A., Kalsbeek, Andries, Pijl, Hanno
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518481/
https://www.ncbi.nlm.nih.gov/pubmed/18544708
http://dx.doi.org/10.2337/db07-1658