The Fatty Acid Receptor GPR40 Plays a Role in Insulin Secretion In Vivo After High-Fat Feeding

OBJECTIVE—The G-protein–coupled receptor GPR40 is expressed in pancreatic β-cells and is activated by long-chain fatty acids. Gene deletion studies have shown that GPR40 mediates, at least in part, fatty acid–amplification of glucose-induced insulin secretion (GSIS) but is not implicated in GSIS its...

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Detalles Bibliográficos
Autores principales: Kebede, Melkam, Alquier, Thierry, Latour, Martin G., Semache, Meriem, Tremblay, Caroline, Poitout, Vincent
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518494/
https://www.ncbi.nlm.nih.gov/pubmed/18559658
http://dx.doi.org/10.2337/db08-0553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518494/
https://www.ncbi.nlm.nih.gov/pubmed/18559658
http://dx.doi.org/10.2337/db08-0553

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