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Pericyte Migration: A Novel Mechanism of Pericyte Loss in Experimental Diabetic Retinopathy

OBJECTIVE— The mechanism underlying pericyte loss during incipient diabetic retinopathy remains controversial. Hyperglycemia induces angiopoietin-2 (Ang-2) transcription, which modulates capillary pericyte coverage. In this study, we assessed loss of pericyte subgroups and the contribution of Ang-2...

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Detalles Bibliográficos
Autores principales: Pfister, Frederick, Feng, Yuxi, vom Hagen, Franziska, Hoffmann, Sigrid, Molema, Grietje, Hillebrands, Jan-Luuk, Shani, Moshe, Deutsch, Urban, Hammes, Hans-Peter
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518502/
https://www.ncbi.nlm.nih.gov/pubmed/18559662
http://dx.doi.org/10.2337/db08-0325