Evaluating the Role of LPIN1 Variation in Insulin Resistance, Body Weight, and Human Lipodystrophy in U.K. Populations

OBJECTIVE— Loss of lipin 1 activity causes lipodystrophy and insulin resistance in the fld mouse, and LPIN1 expression and common genetic variation were recently suggested to influence adiposity and insulin sensitivity in humans. We aimed to conduct a comprehensive association study to clarify the i...

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Detalles Bibliográficos
Autores principales: Fawcett, Katherine A., Grimsey, Neil, Loos, Ruth J.F., Wheeler, Eleanor, Daly, Allan, Soos, Maria, Semple, Robert, Syddall, Holly, Cooper, Cyrus, Siniossoglou, Symeon, O'Rahilly, Stephen, Wareham, Nicholas J., Barroso, Inês
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518506/
https://www.ncbi.nlm.nih.gov/pubmed/18591397
http://dx.doi.org/10.2337/db08-0422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518506/
https://www.ncbi.nlm.nih.gov/pubmed/18591397
http://dx.doi.org/10.2337/db08-0422

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