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Coordinate Regulation of G Protein Signaling via Dynamic Interactions of Receptor and GAP
Signal output from receptor–G-protein–effector modules is a dynamic function of the nucleotide exchange activity of the receptor, the GTPase-accelerating activity of GTPase-activating proteins (GAPs), and their interactions. GAPs may inhibit steady-state signaling but may also accelerate deactivatio...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518520/ https://www.ncbi.nlm.nih.gov/pubmed/18716678 http://dx.doi.org/10.1371/journal.pcbi.1000148 |