Cargando…
Coordinate Regulation of G Protein Signaling via Dynamic Interactions of Receptor and GAP
Signal output from receptor–G-protein–effector modules is a dynamic function of the nucleotide exchange activity of the receptor, the GTPase-accelerating activity of GTPase-activating proteins (GAPs), and their interactions. GAPs may inhibit steady-state signaling but may also accelerate deactivatio...
Autores principales: | Turcotte, Marc, Tang, Wei, Ross, Elliott M. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518520/ https://www.ncbi.nlm.nih.gov/pubmed/18716678 http://dx.doi.org/10.1371/journal.pcbi.1000148 |
Ejemplares similares
-
Homer 2 tunes G protein–coupled receptors stimulus intensity by regulating RGS proteins and PLCβ GAP activities
por: Shin, Dong Min, et al.
Publicado: (2003) -
Modulation of receptor dynamics by the regulator of G protein signaling Sst2
por: Venkatapurapu, Sai Phanindra, et al.
Publicado: (2015) -
Regulating G protein-coupled receptors by topological inversion
por: Denard, Bray, et al.
Publicado: (2019) -
Activation Biosensor for G Protein-Coupled Receptors: A FRET-Based m1 Muscarinic Activation Sensor That Regulates G(q)
por: Chang, Seungwoo, et al.
Publicado: (2012) -
G Protein-coupled receptors: Multi-turnover GDP/GTP exchange catalysis on heterotrimeric G proteins
por: Ross, Elliott M
Publicado: (2014)