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P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis
BACKGROUND: The purinergic receptor P2x7 is expressed on myeloid cells as well as on CNS glial cells, and P2x7 activation has been shown to increase both glial and T-cell activation. These properties suggest a role in the development of autoimmune disease including multiple sclerosis. METHODS: The a...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518548/ https://www.ncbi.nlm.nih.gov/pubmed/18691411 http://dx.doi.org/10.1186/1742-2094-5-33 |