Segmental Duplications Arise from Pol32-Dependent Repair of Broken Forks through Two Alternative Replication-Based Mechanisms

The propensity of segmental duplications (SDs) to promote genomic instability is of increasing interest since their involvement in numerous human genomic diseases and cancers was revealed. However, the mechanism(s) responsible for their appearance remain mostly speculative. Here, we show that in bud...

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Detalles Bibliográficos
Autores principales: Payen, Celia, Koszul, Romain, Dujon, Bernard, Fischer, Gilles
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518615/
https://www.ncbi.nlm.nih.gov/pubmed/18773114
http://dx.doi.org/10.1371/journal.pgen.1000175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518615/
https://www.ncbi.nlm.nih.gov/pubmed/18773114
http://dx.doi.org/10.1371/journal.pgen.1000175

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