Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied

When the spindle assembly checkpoint (SAC) cannot be satisfied, cells exit mitosis via mitotic slippage. In microtubule (MT) poisons, slippage requires cyclin B proteolysis, and it appears to be accelerated in drug concentrations that allow some MT assembly. To determine if MTs accelerate slippage,...

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Detalles Bibliográficos
Autores principales: Brito, Daniela A., Yang, Zhenye, Rieder, Conly L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518701/
https://www.ncbi.nlm.nih.gov/pubmed/18710927
http://dx.doi.org/10.1083/jcb.200805072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518701/
https://www.ncbi.nlm.nih.gov/pubmed/18710927
http://dx.doi.org/10.1083/jcb.200805072

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