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Mechanotransduction in an extracted cell model: Fyn drives stretch- and flow-elicited PECAM-1 phosphorylation

Mechanosensing followed by mechanoresponses by cells is well established, but the mechanisms by which mechanical force is converted into biochemical events are poorly understood. Vascular endothelial cells (ECs) exhibit flow- and stretch-dependent responses and are widely used as a model for studyin...

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Detalles Bibliográficos
Autores principales: Chiu, Yi-Jen, McBeath, Elena, Fujiwara, Keigi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518713/
https://www.ncbi.nlm.nih.gov/pubmed/18710921
http://dx.doi.org/10.1083/jcb.200801062