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Mechanotransduction in an extracted cell model: Fyn drives stretch- and flow-elicited PECAM-1 phosphorylation
Mechanosensing followed by mechanoresponses by cells is well established, but the mechanisms by which mechanical force is converted into biochemical events are poorly understood. Vascular endothelial cells (ECs) exhibit flow- and stretch-dependent responses and are widely used as a model for studyin...
Autores principales: | Chiu, Yi-Jen, McBeath, Elena, Fujiwara, Keigi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518713/ https://www.ncbi.nlm.nih.gov/pubmed/18710921 http://dx.doi.org/10.1083/jcb.200801062 |
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