Cargando…

Inferring Condition-Specific Modulation of Transcription Factor Activity in Yeast through Regulon-Based Analysis of Genomewide Expression

BACKGROUND: A key goal of systems biology is to understand how genomewide mRNA expression levels are controlled by transcription factors (TFs) in a condition-specific fashion. TF activity is frequently modulated at the post-translational level through ligand binding, covalent modification, or change...

Descripción completa

Detalles Bibliográficos
Autores principales: Boorsma, André, Lu, Xiang-Jun, Zakrzewska, Anna, Klis, Frans M., Bussemaker, Harmen J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518834/
https://www.ncbi.nlm.nih.gov/pubmed/18769540
http://dx.doi.org/10.1371/journal.pone.0003112